Orthobiologics are some of the newest minimally invasiv options for treatment of musculoskeletal diseases and injuries. These treatments involve the introduction or stimulation of mesenchymal stem cels (MSC), which help your own body to repair damaged cells and reduce inflammation.
Mesenchymal stem cells (MSC), otherwise known as mesenchymal signaling cells, are derived from differentiation of perivascular or mural cells called pericytes. These pericytes migrate into the diseased or injured tissue to assist with repair and reduction of pain.
These effects are not immediate but may take several weeks to promote a response. How fast you recover depends ultimately on the condition and your body’s response.
Platelets are concentrated from a patient’s own drawn blood. This concentrate is injected into the involved area. The activated platelets release growth factors and other proteins which mobilize the MSC’s.
Bone marrow is a rich source of stem cells and other growth factors. Bone marrow is aspirated from the hip or tibia and concentrated. This concentrate is then injected into the involved area or used in conjunction with surgery.
Adipose tissue is also a rich source of stem cells and healing proteins. It can be harvested from the abdomen and injected into the involved area.
Amniotic tissue is safe and commonly available for use in disease or injured tissues with many of the same properties and effects without any harvest necessary.